Basic guide: Postural Orthostatic Tachycardia Syndrome (POTS)

Postural Orthostatic Tachycardia Syndrome (POTS)

POTS is also known as Chronic Orthostatic Intolerance, Postural Tachycardia Syndrome, “The Grinch Syndrome” (like the Dr Seuss character whose heart was “two sizes too small”), Soldier’s Heart, DaCosta’s Syndrome, Chronic Orthostatic Intolerance, Orthostatic Tachycardia and Postural Tachycardia Syndrome.
What is Postural Tachycardia Syndrome?

Postural Orthostatic Tachycardia Syndrome is a disorder marked by an excessive heart rate and flu-like symptoms when standing or a given level of exercise.

Basic guide Postural Orthostatic Tachycardia Syndrome (POTS)It is is one of a group of disorders that have orthostatic intolerance (OI) as their primary symptom. OI describes a condition in which an excessively reduced volume of blood returns to the heart after an individual stands up from a lying down position.

The primary symptom of OI is lightheadedness or fainting. In POTS, the lightheadedness or fainting is also accompanied by a rapid increase in heartbeat of more than 30 beats per minute, or a heart rate that exceeds 120 beats per minute, within 10 minutes of rising. The faintness or lightheadedness of POTS are relieved by lying down again.

Anyone at any age can develop POTS, but the majority of individuals affected (between 75 and 80 percent) are women between the ages of 15 to 50 years of age. Some women report an increase in episodes of POTS right before their menstrual periods.

POTS often begins after a pregnancy, major surgery, trauma, or a viral illness. It may make individuals unable to exercise because the activity brings on fainting spells or dizziness.

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Doctors aren’t sure yet what causes the reduced return of blood to the heart that occurs in OI, or why the heart begins to beat so rapidly in POTS.

Current thinking is that there are a number of mechanisms.  Some patients have peripheral denervation (neuropathic POTS); some have symptoms that are due to sustained or parosyxmal overactivity of the sympathetic nervous system (hyperadrenergic POTS); and some individuals have POTS dominated by features of deconditioning.

Is there any treatment?

Therapies for POTS are targeted at relieving low blood volume or regulating circulatory problems that could be causing the disorder. No single treatment has been found to be effect for all. A number of drugs seem to be effective in the short term, but whether they help in long term is uncertain. Simple interventions such as adding extra salt to the diet and attention to adequate fluid intake are often effective.



The drugs fludrocortisone (for those on a high salt diet) and midodrine in low doses are often used to increase blood volume and narrow blood vessels. Drinking 16 ounces of water (2 glassfuls) before getting up can also help raise blood pressure. Some individuals are helped by beta receptor blocking agents. There is some evidence that an exercise program can gradually improve orthostatic tolerance.

What is the prognosis?

POTS may follow a relapsing-remitting course, in which symptoms come and go, for years. In most cases (approximately 80 percent), an individual with POTS improves and becomes functional, although some residual symptoms are common.

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There has been research about POTS and Lyme Disease, as well as a possible connection between the disorder and a vitamin B-12 deficiency.

See many of the latest medical studies about POTS here.

For more help

A couple organizations you might contact for help with POTS include…

National Dysautonomia Research Foundation
P.O. Box 301; Red Wing, MN 55066-0301
Tel: 651-327-0367 / Fax: 651-267-0524
ndrf.org

Dysautonomia Youth Network of America, Inc.
1301 Greengate Court; Waldorf, MD 20601
Tel: 301-705-6995 / Fax: 301-638-DYNA
dynainc.org



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